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TMEM41B Is a Pan-flavivirus Host Factor

Flaviviruses pose a constant threat to human health. These RNA viruses are transmitted by the bite of infected mosquitoes and ticks and regularly cause outbreaks. To identify host factors required for flavivirus infection, we performed full-genome loss of function CRISPR-Cas9 screens. Based on these...

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Detalles Bibliográficos
Autores principales: Hoffmann, H.-Heinrich, Schneider, William M., Rozen-Gagnon, Kathryn, Miles, Linde A., Schuster, Felix, Razooky, Brandon, Jacobson, Eliana, Wu, Xianfang, Yi, Soon, Rudin, Charles M., MacDonald, Margaret R., McMullan, Laura K., Poirier, John T., Rice, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954666/
https://www.ncbi.nlm.nih.gov/pubmed/33338421
http://dx.doi.org/10.1016/j.cell.2020.12.005