Advances in monitoring and control of refolding kinetics combining PAT and modeling

ABSTRACT: Overexpression of recombinant proteins in Escherichia coli results in misfolded and non-active protein aggregates in the cytoplasm, so-called inclusion bodies (IB). In recent years, a change in the mindset regarding IBs could be observed: IBs are no longer considered an unwanted waste prod...

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Detalles Bibliográficos
Autores principales: Pauk, Jan Niklas, Raju Palanisamy, Janani, Kager, Julian, Koczka, Krisztina, Berghammer, Gerald, Herwig, Christoph, Veiter, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Mini-Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954745/
https://www.ncbi.nlm.nih.gov/pubmed/33598720
http://dx.doi.org/10.1007/s00253-021-11151-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954745/
https://www.ncbi.nlm.nih.gov/pubmed/33598720
http://dx.doi.org/10.1007/s00253-021-11151-y

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