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Estimating copy number using next-generation sequencing to determine ERBB2 amplification status

Assessing Erb-b2 receptor tyrosine kinase 2 (ERBB2) amplification status in breast and gastric cancer is necessary for deciding the best therapeutic strategy. Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) are currently used for assessing protein levels and gene copy number...

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Detalles Bibliográficos
Autores principales: Nakamura, Kohei, Aimono, Eriko, Oba, Junna, Hayashi, Hideyuki, Tanishima, Shigeki, Hayashida, Tetsu, Chiyoda, Tatsuyuki, Kosaka, Takeo, Hishida, Tomoyuki, Kawakubo, Hirohumi, Kitago, Minoru, Okabayashi, Koji, Funakoshi, Takeru, Okita, Hajime, Ikeda, Sadakatsu, Takaishi, Hiromasa, Nishihara, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954749/
https://www.ncbi.nlm.nih.gov/pubmed/33710417
http://dx.doi.org/10.1007/s12032-021-01482-1