Protein context shapes the specificity of SH3 domain-mediated interactions in vivo

Protein–protein interactions (PPIs) between modular binding domains and their target peptide motifs are thought to largely depend on the intrinsic binding specificities of the domains. The large family of SRC Homology 3 (SH3) domains contribute to cellular processes via their ability to support such...

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Detalles Bibliográficos
Autores principales: Dionne, Ugo, Bourgault, Émilie, Dubé, Alexandre K., Bradley, David, Chartier, François J. M., Dandage, Rohan, Dibyachintan, Soham, Després, Philippe C., Gish, Gerald D., Pham, N. T. Hang, Létourneau, Myriam, Lambert, Jean-Philippe, Doucet, Nicolas, Bisson, Nicolas, Landry, Christian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954794/
https://www.ncbi.nlm.nih.gov/pubmed/33712617
http://dx.doi.org/10.1038/s41467-021-21873-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954794/
https://www.ncbi.nlm.nih.gov/pubmed/33712617
http://dx.doi.org/10.1038/s41467-021-21873-2

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