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A computer-guided design tool to increase the efficiency of cellular conversions

Human cell conversion technology has become an important tool for devising new cell transplantation therapies, generating disease models and testing gene therapies. However, while transcription factor over-expression-based methods have shown great promise in generating cell types in vitro, they ofte...

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Detalles Bibliográficos
Autores principales: Jung, Sascha, Appleton, Evan, Ali, Muhammad, Church, George M., del Sol, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954801/
https://www.ncbi.nlm.nih.gov/pubmed/33712564
http://dx.doi.org/10.1038/s41467-021-21801-4