Cyst formation in proximal renal tubules caused by dysfunction of the microtubule minus-end regulator CAMSAP3

Epithelial cells organize an ordered array of non-centrosomal microtubules, the minus ends of which are regulated by CAMSAP3. The role of these microtubules in epithelial functions, however, is poorly understood. Here, we show that the kidneys of mice in which Camsap3 is mutated develop cysts at the...

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Detalles Bibliográficos
Autores principales: Mitsuhata, Yuto, Abe, Takaya, Misaki, Kazuyo, Nakajima, Yuna, Kiriya, Keita, Kawasaki, Miwa, Kiyonari, Hiroshi, Takeichi, Masatoshi, Toya, Mika, Sato, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954811/
https://www.ncbi.nlm.nih.gov/pubmed/33712686
http://dx.doi.org/10.1038/s41598-021-85416-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954811/
https://www.ncbi.nlm.nih.gov/pubmed/33712686
http://dx.doi.org/10.1038/s41598-021-85416-x

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