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The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis

Casein kinase 2 (CK2) is a pleiotropic kinase phosphorylating substrates in different cellular compartments in eukaryotes. In the malaria parasite Plasmodium falciparum, PfCK2 is vital for asexual proliferation of blood-stage parasites. Here, we applied CRISPR/Cas9-based gene editing to investigate...

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Detalles Bibliográficos
Autores principales: Hitz, Eva, Grüninger, Olivia, Passecker, Armin, Wyss, Matthias, Scheurer, Christian, Wittlin, Sergio, Beck, Hans-Peter, Brancucci, Nicolas M. B., Voss, Till S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954856/
https://www.ncbi.nlm.nih.gov/pubmed/33712726
http://dx.doi.org/10.1038/s42003-021-01873-0