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Dynamic relocalization of cytosolic type III secretion system components prevents premature protein secretion at low external pH

Many bacterial pathogens use a type III secretion system (T3SS) to manipulate host cells. Protein secretion by the T3SS injectisome is activated upon contact to any host cell, and it has been unclear how premature secretion is prevented during infection. Here we report that in the gastrointestinal p...

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Detalles Bibliográficos
Autores principales: Wimmi, Stephan, Balinovic, Alexander, Jeckel, Hannah, Selinger, Lisa, Lampaki, Dimitrios, Eisemann, Emma, Meuskens, Ina, Linke, Dirk, Drescher, Knut, Endesfelder, Ulrike, Diepold, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954860/
https://www.ncbi.nlm.nih.gov/pubmed/33712575
http://dx.doi.org/10.1038/s41467-021-21863-4