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Dynamic relocalization of cytosolic type III secretion system components prevents premature protein secretion at low external pH
Many bacterial pathogens use a type III secretion system (T3SS) to manipulate host cells. Protein secretion by the T3SS injectisome is activated upon contact to any host cell, and it has been unclear how premature secretion is prevented during infection. Here we report that in the gastrointestinal p...
Autores principales: | Wimmi, Stephan, Balinovic, Alexander, Jeckel, Hannah, Selinger, Lisa, Lampaki, Dimitrios, Eisemann, Emma, Meuskens, Ina, Linke, Dirk, Drescher, Knut, Endesfelder, Ulrike, Diepold, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954860/ https://www.ncbi.nlm.nih.gov/pubmed/33712575 http://dx.doi.org/10.1038/s41467-021-21863-4 |
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