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Joint profiling of histone modifications and transcriptome in single cells from mouse brain

Genome-wide profiling of histone modifications can reveal not only the location and activity state of regulatory elements, but also the regulatory mechanisms involved in cell-type-specific gene expression during development and disease pathology. Conventional assays to profile histone modifications...

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Detalles Bibliográficos
Autores principales: Zhu, Chenxu, Zhang, Yanxiao, Li, Yang Eric, Lucero, Jacinta, Behrens, M. Margarita, Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954905/
https://www.ncbi.nlm.nih.gov/pubmed/33589836
http://dx.doi.org/10.1038/s41592-021-01060-3