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Joint profiling of histone modifications and transcriptome in single cells from mouse brain
Genome-wide profiling of histone modifications can reveal not only the location and activity state of regulatory elements, but also the regulatory mechanisms involved in cell-type-specific gene expression during development and disease pathology. Conventional assays to profile histone modifications...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954905/ https://www.ncbi.nlm.nih.gov/pubmed/33589836 http://dx.doi.org/10.1038/s41592-021-01060-3 |