Decoding the Protein Composition of Whole Nucleosomes with Nuc-MS

Current proteomics approaches disassemble and digest nucleosome particles, blurring the readout of the “histone code”. To preserve nucleosome-level information, we developed Nuc-MS which displays the landscape of histone variants and their PTMs in a single mass spectrum. Combined with immunoprecipit...

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Detalles Bibliográficos
Autores principales: Schachner, Luis F., Jooβ, Kevin, Morgan, Marc A., Piunti, Andrea, Meiners, Matthew J., Kafader, Jared O., Lee, Alexander S., Iwanaszko, Marta, Cheek, Marcus A., Burg, Jonathan M., Howard, Sarah A., Keogh, Michael-Christopher, Shilatifard, Ali, Kelleher, Neil L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954958/
https://www.ncbi.nlm.nih.gov/pubmed/33589837
http://dx.doi.org/10.1038/s41592-020-01052-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954958/
https://www.ncbi.nlm.nih.gov/pubmed/33589837
http://dx.doi.org/10.1038/s41592-020-01052-9

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