Cargando…

Decoding the Protein Composition of Whole Nucleosomes with Nuc-MS

Current proteomics approaches disassemble and digest nucleosome particles, blurring the readout of the “histone code”. To preserve nucleosome-level information, we developed Nuc-MS which displays the landscape of histone variants and their PTMs in a single mass spectrum. Combined with immunoprecipit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schachner, Luis F., Jooβ, Kevin, Morgan, Marc A., Piunti, Andrea, Meiners, Matthew J., Kafader, Jared O., Lee, Alexander S., Iwanaszko, Marta, Cheek, Marcus A., Burg, Jonathan M., Howard, Sarah A., Keogh, Michael-Christopher, Shilatifard, Ali, Kelleher, Neil L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954958/ https://www.ncbi.nlm.nih.gov/pubmed/33589837 http://dx.doi.org/10.1038/s41592-020-01052-9

Ejemplares similares

iNucs: inter-nucleosome interactions
por: Oveisi, Mehrdad, et al.
Publicado: (2021)

NucPosDB: a database of nucleosome positioning in vivo and nucleosomics of cell-free DNA
por: Shtumpf, Mariya, et al.
Publicado: (2022)

A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer
por: Morgan, Marc A.J., et al.
Publicado: (2021)

NucMap: a database of genome-wide nucleosome positioning map across species
por: Zhao, Yongbing, et al.
Publicado: (2019)

NucHMM: a method for quantitative modeling of nucleosome organization identifying functional nucleosome states distinctly associated with splicing potentiality
por: Fang, Kun, et al.
Publicado: (2021)

iNuc-PhysChem: A Sequence-Based Predictor for Identifying Nucleosomes via Physicochemical Properties
por: Chen, Wei, et al.
Publicado: (2012)

NucVoter: A Voting Algorithm for Reliable Nucleosome Prediction Using Next-Generation Sequencing Data
por: Byeon, Boseon
Publicado: (2013)

Quantitative HPLC-MS/MS determination of Nuc, the active metabolite of remdesivir, and its pharmacokinetics in rat
por: Du, Ping, et al.
Publicado: (2021)

Decoding the centromeric nucleosome through CENP-N
por: Pentakota, Satyakrishna, et al.
Publicado: (2017)

Exploring the Binding Mechanism and Dynamics of EndoMS/NucS to Mismatched dsDNA
por: Zhang, Yanjun, et al.
Publicado: (2019)

Control of Genome Stability by EndoMS/NucS-Mediated Non-Canonical Mismatch Repair
por: Cebrián-Sastre, Esmeralda, et al.
Publicado: (2021)

Characterization of NucPNP and NucV involved in the early steps of nucleocidin biosynthesis in Streptomyces calvus
por: Ngivprom, Utumporn, et al.
Publicado: (2021)

New sensations in molecular diagnostics—NucliSENS easyMAG extraction platform and NucliSENs EasyQ assays
por: Troesch, A.
Publicado: (2006)

Functional Analysis of the NucS/EndoMS of the Hyperthermophilic Archaeon Sulfolobus islandicus REY15A
por: Ahmad, Sohail, et al.
Publicado: (2020)

Quantification of citrullinated histones: Development of an improved assay to reliably quantify nucleosomal H3Cit in human plasma
por: Thålin, Charlotte, et al.
Publicado: (2020)

A small UTX stabilization domain of Trr is conserved within mammalian MLL3-4/COMPASS and is sufficient to rescue loss of viability in null animals
por: Rickels, Ryan, et al.
Publicado: (2020)

Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins
por: LeRoy, Gary, et al.
Publicado: (2012)

NucliTrack: an integrated nuclei tracking application
por: Cooper, Sam, et al.
Publicado: (2017)

Activation of the mismatch-specific endonuclease EndoMS/NucS by the replication clamp is required for high fidelity DNA replication
por: Ishino, Sonoko, et al.
Publicado: (2018)

A novel DNA sequence periodicity decodes nucleosome positioning
por: Chen, Kaifu, et al.
Publicado: (2008)

The Effects of Addition of Mononucleotides on Sma nuc Endonuclease Activity
por: Romanova, Julia, et al.
Publicado: (2012)

Bacterial EndoMS/NucS acts as a clamp-mediated mismatch endonuclease to prevent asymmetric accumulation of replication errors
por: Takemoto, Norihiko, et al.
Publicado: (2018)

NucEnvDB: A Database of Nuclear Envelope Proteins and Their Interactions
por: Baltoumas, Fotis A., et al.
Publicado: (2023)

Role of nuc gene in Staphylococcus aureus to phagocytic activity in different cattle infections
por: Ibraheim, Hanaa Khaleel, et al.
Publicado: (2023)

NucBase, an easy to use read mapper for small RNAs
por: Dufourt, Jeremy, et al.
Publicado: (2013)

Crystal structure of NucB, a biofilm-degrading endonuclease
por: Baslé, Arnaud, et al.
Publicado: (2018)

EPEN-20. EZHIP/CATACOMB COOPERATES WITH PDGF-A AND p53 LOSS TO GENERATE A GENETICALLY ENGINEERED MOUSE MODEL FOR POSTERIOR FOSSA A EPENDYMOMA
por: Kagan, Emily, et al.
Publicado: (2020)

Staphylococcus aureus Nuc2 Is a Functional, Surface-Attached Extracellular Nuclease
por: Kiedrowski, Megan R., et al.
Publicado: (2014)

Structural basis for the substrate selectivity of Helicobacter pylori NucT nuclease activity
por: Celma, Louisa, et al.
Publicado: (2017)

Effects of H3.3G34V mutation on genomic H3K36 and H3K27 methylation patterns in isogenic pediatric glioma cells
por: Huang, Tina Yi-Ting, et al.
Publicado: (2020)

In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells
Publicado: (1990)

New Insights Into DNA Repair Revealed by NucS Endonucleases From Hyperthermophilic Archaea
por: Zhang, Likui, et al.
Publicado: (2020)

Evaluation of the new NucliSens easyMAG(®) nucleic acid extraction system
por: Bossart, W., et al.
Publicado: (2006)

The Overexpression of NUC Promotes Development and Increases Resistance to Nitrogen Deficiency in Arabidopsis thaliana
por: Ling, Jing, et al.
Publicado: (2021)

NUC041, a Prodrug of the DNA Methytransferase Inhibitor 5-aza-2′,2′-Difluorodeoxycytidine (NUC013), Leads to Tumor Regression in a Model of Non-Small Cell Lung Cancer
por: Daifuku, Richard, et al.
Publicado: (2018)

Genome Editing Outcomes Reveal Mycobacterial NucS Participates in a Short-Patch Repair of DNA Mismatches
por: Islam, Tanjina, et al.
Publicado: (2023)

LC–MS/MS-based quantitative study of the acyl group- and site-selectivity of human sirtuins to acylated nucleosomes
por: Tanabe, Kana, et al.
Publicado: (2018)

NucAmino: a nucleotide to amino acid alignment optimized for virus gene sequences
por: Tzou, Philip L., et al.
Publicado: (2017)

NucDiff: in-depth characterization and annotation of differences between two sets of DNA sequences
por: Khelik, Ksenia, et al.
Publicado: (2017)

Comparison of eMAG™ versus NucliSENS(®) EasyMAG(®) performance on clinical specimens
por: Garcia, Magali, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_krgb96581j07g3t42ajms8qu7d