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The amyloid structure of mouse RIPK3 (receptor interacting protein kinase 3) in cell necroptosis

RIPK3 amyloid complex plays crucial roles during TNF-induced necroptosis and in response to immune defense in both human and mouse. Here, we have structurally characterized mouse RIPK3 homogeneous self-assembly using solid-state NMR, revealing a well-ordered N-shaped amyloid core structure featured...

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Detalles Bibliográficos
Autores principales: Wu, Xia-lian, Hu, Hong, Dong, Xing-qi, Zhang, Jing, Wang, Jian, Schwieters, Charles D., Liu, Jing, Wu, Guo-xiang, Li, Bing, Lin, Jing-yu, Wang, Hua-yi, Lu, Jun-xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955032/
https://www.ncbi.nlm.nih.gov/pubmed/33712586
http://dx.doi.org/10.1038/s41467-021-21881-2