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The amyloid structure of mouse RIPK3 (receptor interacting protein kinase 3) in cell necroptosis
RIPK3 amyloid complex plays crucial roles during TNF-induced necroptosis and in response to immune defense in both human and mouse. Here, we have structurally characterized mouse RIPK3 homogeneous self-assembly using solid-state NMR, revealing a well-ordered N-shaped amyloid core structure featured...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955032/ https://www.ncbi.nlm.nih.gov/pubmed/33712586 http://dx.doi.org/10.1038/s41467-021-21881-2 |