Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain

We report a metabolomic analysis of Streptomyces sp. ID38640, a soil isolate that produces the bacterial RNA polymerase inhibitor pseudouridimycin. The analysis was performed on the wild type, on three newly constructed and seven previously reported mutant strains disabled in different genes require...

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Detalles Bibliográficos
Autores principales: Iorio, Marianna, Davatgarbenam, Sahar, Serina, Stefania, Criscenzo, Paolo, Zdouc, Mitja M., Simone, Matteo, Maffioli, Sonia I., Ebright, Richard H., Donadio, Stefano, Sosio, Margherita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955054/
https://www.ncbi.nlm.nih.gov/pubmed/33712632
http://dx.doi.org/10.1038/s41598-021-84833-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955054/
https://www.ncbi.nlm.nih.gov/pubmed/33712632
http://dx.doi.org/10.1038/s41598-021-84833-2

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