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Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain
We report a metabolomic analysis of Streptomyces sp. ID38640, a soil isolate that produces the bacterial RNA polymerase inhibitor pseudouridimycin. The analysis was performed on the wild type, on three newly constructed and seven previously reported mutant strains disabled in different genes require...
Autores principales: | Iorio, Marianna, Davatgarbenam, Sahar, Serina, Stefania, Criscenzo, Paolo, Zdouc, Mitja M., Simone, Matteo, Maffioli, Sonia I., Ebright, Richard H., Donadio, Stefano, Sosio, Margherita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955054/ https://www.ncbi.nlm.nih.gov/pubmed/33712632 http://dx.doi.org/10.1038/s41598-021-84833-2 |
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