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Maternal antibodies facilitate Amyloid-β clearance by activating Fc-receptor-Syk-mediated phagocytosis

Maternal antibodies (MAbs) protect against infections in immunologically-immature neonates. Maternally transferred immunity may also be harnessed to target diseases associated with endogenous protein misfolding and aggregation, such as Alzheimer’s disease (AD) and AD-pathology in Down syndrome (DS)....

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Detalles Bibliográficos
Autores principales: Illouz, Tomer, Nicola, Raneen, Ben-Shushan, Linoy, Madar, Ravit, Biragyn, Arya, Okun, Eitan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955073/
https://www.ncbi.nlm.nih.gov/pubmed/33712740
http://dx.doi.org/10.1038/s42003-021-01851-6