Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia

Anemias of chronic disease and inflammation (ACDI) result from restricted iron delivery to erythroid progenitors. The current studies reveal an organellar response in erythroid iron restriction consisting of disassembly of the microtubule cytoskeleton and associated Golgi disruption. Isocitrate supp...

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Detalles Bibliográficos
Autores principales: Goldfarb, Adam N., Freeman, Katie C., Sahu, Ranjit K., Elagib, Kamaleldin E., Holy, Maja, Arneja, Abhinav, Polanowska-Grabowska, Renata, Gru, Alejandro A., White, Zollie, Khalil, Shadi, Kerins, Michael J., Ooi, Aikseng, Leitinger, Norbert, Luckey, Chance John, Delehanty, Lorrie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955080/
https://www.ncbi.nlm.nih.gov/pubmed/33712594
http://dx.doi.org/10.1038/s41467-021-21938-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955080/
https://www.ncbi.nlm.nih.gov/pubmed/33712594
http://dx.doi.org/10.1038/s41467-021-21938-2

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