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Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia
Anemias of chronic disease and inflammation (ACDI) result from restricted iron delivery to erythroid progenitors. The current studies reveal an organellar response in erythroid iron restriction consisting of disassembly of the microtubule cytoskeleton and associated Golgi disruption. Isocitrate supp...
Autores principales: | Goldfarb, Adam N., Freeman, Katie C., Sahu, Ranjit K., Elagib, Kamaleldin E., Holy, Maja, Arneja, Abhinav, Polanowska-Grabowska, Renata, Gru, Alejandro A., White, Zollie, Khalil, Shadi, Kerins, Michael J., Ooi, Aikseng, Leitinger, Norbert, Luckey, Chance John, Delehanty, Lorrie L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955080/ https://www.ncbi.nlm.nih.gov/pubmed/33712594 http://dx.doi.org/10.1038/s41467-021-21938-2 |
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