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Interplay of BAF and MLL4 promotes cell type-specific enhancer activation
Cell type-specific enhancers are activated by coordinated actions of lineage-determining transcription factors (LDTFs) and chromatin regulators. The SWI/SNF chromatin remodeling complex BAF and the histone H3K4 methyltransferase MLL4 (KMT2D) are both implicated in enhancer activation. However, the i...
Autores principales: | Park, Young-Kwon, Lee, Ji-Eun, Yan, Zhijiang, McKernan, Kaitlin, O’Haren, Tommy, Wang, Weidong, Peng, Weiqun, Ge, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955098/ https://www.ncbi.nlm.nih.gov/pubmed/33712604 http://dx.doi.org/10.1038/s41467-021-21893-y |
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