Cargando…
Cryo-EM structure of amyloid fibrils formed by the entire low complexity domain of TDP-43
Amyotrophic lateral sclerosis and several other neurodegenerative diseases are associated with brain deposits of amyloid-like aggregates formed by the C-terminal fragments of TDP-43 that contain the low complexity domain of the protein. Here, we report the cryo-EM structure of amyloid formed from th...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955110/ https://www.ncbi.nlm.nih.gov/pubmed/33712624 http://dx.doi.org/10.1038/s41467-021-21912-y |