Defining the root cause of reduced H1N1 live attenuated influenza vaccine effectiveness: low viral fitness leads to inter-strain competition

In the 2013–14 and 2015–16 influenza seasons, reduced vaccine effectiveness (VE) was observed for the H1N1 component of the FluMist quadrivalent live attenuated influenza vaccine (QLAIV) in the USA, leading to loss of Advisory Committee on Immunization Practices recommendation. Here we demonstrate i...

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Detalles Bibliográficos
Autores principales: Dibben, Oliver, Crowe, Jonathan, Cooper, Shaun, Hill, Laura, Schewe, Katarzyna E., Bright, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955111/
https://www.ncbi.nlm.nih.gov/pubmed/33712628
http://dx.doi.org/10.1038/s41541-021-00300-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955111/
https://www.ncbi.nlm.nih.gov/pubmed/33712628
http://dx.doi.org/10.1038/s41541-021-00300-z

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