Discovery of fungal surface NADases predominantly present in pathogenic species

Nicotinamide adenine dinucleotide (NAD) is a key molecule in cellular bioenergetics and signalling. Various bacterial pathogens release NADase enzymes into the host cell that deplete the host’s NAD(+) pool, thereby causing rapid cell death. Here, we report the identification of NADases on the surfac...

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Detalles Bibliográficos
Autores principales: Strømland, Øyvind, Kallio, Juha P., Pschibul, Annica, Skoge, Renate H., Harðardóttir, Hulda M., Sverkeli, Lars J., Heinekamp, Thorsten, Kniemeyer, Olaf, Migaud, Marie, Makarov, Mikhail V., Gossmann, Toni I., Brakhage, Axel A., Ziegler, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955114/
https://www.ncbi.nlm.nih.gov/pubmed/33712585
http://dx.doi.org/10.1038/s41467-021-21307-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955114/
https://www.ncbi.nlm.nih.gov/pubmed/33712585
http://dx.doi.org/10.1038/s41467-021-21307-z

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