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Aptardi predicts polyadenylation sites in sample-specific transcriptomes using high-throughput RNA sequencing and DNA sequence

Annotation of polyadenylation sites from short-read RNA sequencing alone is a challenging computational task. Other algorithms rooted in DNA sequence predict potential polyadenylation sites; however, in vivo expression of a particular site varies based on a myriad of conditions. Here, we introduce a...

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Detalles Bibliográficos
Autores principales: Lusk, Ryan, Stene, Evan, Banaei-Kashani, Farnoush, Tabakoff, Boris, Kechris, Katerina, Saba, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955126/
https://www.ncbi.nlm.nih.gov/pubmed/33712618
http://dx.doi.org/10.1038/s41467-021-21894-x