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An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism

The signalling pathways underpinning cell growth and invasion use overlapping components, yet how mutually exclusive cellular responses occur is unclear. Here, we report development of 3-Dimensional culture analyses to separately quantify growth and invasion. We identify that alternate variants of I...

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Detalles Bibliográficos
Autores principales: Nacke, Marisa, Sandilands, Emma, Nikolatou, Konstantina, Román-Fernández, Álvaro, Mason, Susan, Patel, Rachana, Lilla, Sergio, Yelland, Tamas, Galbraith, Laura C. A., Freckmann, Eva C., McGarry, Lynn, Morton, Jennifer P., Shanks, Emma, Leung, Hing Y., Markert, Elke, Ismail, Shehab, Zanivan, Sara, Blyth, Karen, Bryant, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955138/
https://www.ncbi.nlm.nih.gov/pubmed/33712589
http://dx.doi.org/10.1038/s41467-021-21847-4