Coxsackievirus B3 Infection Early in Pregnancy Induces Congenital Heart Defects Through Suppression of Fetal Cardiomyocyte Proliferation

BACKGROUND: Coxsackievirus B (CVB) is the most common cause of viral myocarditis. It targets cardiomyocytes through coxsackie and adenovirus receptor, which is highly expressed in the fetal heart. We hypothesized CVB3 can precipitate congenital heart defects when fetal infection occurs during critic...

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Detalles Bibliográficos
Autores principales: Sharma, Vipul, Goessling, Lisa S., Brar, Anoop K., Joshi, Chetanchandra S., Mysorekar, Indira U., Eghtesady, Pirooz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955305/
https://www.ncbi.nlm.nih.gov/pubmed/33440998
http://dx.doi.org/10.1161/JAHA.120.017995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955305/
https://www.ncbi.nlm.nih.gov/pubmed/33440998
http://dx.doi.org/10.1161/JAHA.120.017995

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