Neuraminidases 1 and 3 Trigger Atherosclerosis by Desialylating Low‐Density Lipoproteins and Increasing Their Uptake by Macrophages

BACKGROUND: Chronic vascular disease atherosclerosis starts with an uptake of atherogenic modified low‐density lipoproteins (LDLs) by resident macrophages, resulting in formation of arterial fatty streaks and eventually atheromatous plaques. Increased plasma sialic acid levels, increased neuraminida...

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Detalles Bibliográficos
Autores principales: Demina, Ekaterina P., Smutova, Victoria, Pan, Xuefang, Fougerat, Anne, Guo, Tianlin, Zou, Chunxia, Chakraberty, Radhika, Snarr, Brendan D., Shiao, Tze C., Roy, Rene, Orekhov, Alexander N., Miyagi, Taeko, Laffargue, Muriel, Sheppard, Donald C., Cairo, Christopher W., Pshezhetsky, Alexey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955353/
https://www.ncbi.nlm.nih.gov/pubmed/33554615
http://dx.doi.org/10.1161/JAHA.120.018756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955353/
https://www.ncbi.nlm.nih.gov/pubmed/33554615
http://dx.doi.org/10.1161/JAHA.120.018756

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