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Impact of Sirolimus as a Primary Immunosuppressant on Myocardial Fibrosis and Diastolic Function Following Heart Transplantation

BACKGROUND: Myocardial fibrosis is an important contributor for development of diastolic dysfunction. We investigated the impact of sirolimus as primary immunosuppression on diastolic dysfunction and fibrosis progression among heart transplantation recipients. METHODS AND RESULTS: In 100 heart trans...

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Detalles Bibliográficos
Autores principales: Alnsasra, Hilmi, Asleh, Rabea, Oh, Jae K., Maleszewski, Joseph J., Lerman, Amir, Toya, Takumi, Chandrasekaran, Krishnaswamy, Bois, Melanie C., Kushwaha, Sudhir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955460/
https://www.ncbi.nlm.nih.gov/pubmed/33325244
http://dx.doi.org/10.1161/JAHA.120.018186