Gasdermin D Influence Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway

BACKGROUND: The inflammation and apoptosis of podocytes contribute to the pathological progression of diabetic nephropathy. Gasdermin D (GSDMD) plays an executive role in pyroptosis, but its effect on high-glucose (HG)-induced inflammation and apoptosis remains unclear. The aim of this study was to...

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Detalles Bibliográficos
Autores principales: Li, Huifang, Zhao, Kunxiao, Li, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955578/
https://www.ncbi.nlm.nih.gov/pubmed/33690262
http://dx.doi.org/10.12659/MSM.928411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955578/
https://www.ncbi.nlm.nih.gov/pubmed/33690262
http://dx.doi.org/10.12659/MSM.928411

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