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Tackling Drug Resistance in EGFR Exon 20 Insertion Mutant Lung Cancer

Insertion mutations in exon 20 (Ex20ins) of the epidermal growth factor receptor (EGFR) gene are the largest class of EGFR mutations in non-small cell lung cancer (NSCLC) for which there are currently no approved targeted therapies. NSCLC patients with these mutations do not respond to clinically ap...

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Detalles Bibliográficos
Autores principales: Pacini, Laura, Jenks, Andrew D, Vyse, Simon, Wilding, Christopher P, Arthur, Amani, Huang, Paul H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955704/
https://www.ncbi.nlm.nih.gov/pubmed/33727854
http://dx.doi.org/10.2147/PGPM.S242045