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Gene-activated matrix harboring a miR20a-expressing plasmid promotes rat cranial bone augmentation

Gene-activated matrix (GAM) has a potential usefulness in bone engineering as an alternate strategy for the lasting release of osteogenic proteins but efficient methods to generate non-viral GAM remain to be established. In this study, we investigated whether an atelocollagen-based GAM containing na...

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Detalles Bibliográficos
Autores principales: Shido, Rena, Sumita, Yoshinori, Hara, Masahito, Iwatake, Mayumi, Narahara, Shun, Umebayashi, Mayumi, Miura, Kei-ichiro, Kodama, Yukinobu, Asahina, Izumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955717/
https://www.ncbi.nlm.nih.gov/pubmed/33738113
http://dx.doi.org/10.1093/rb/rbaa060