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Formulation and Characterization of Phytostanol Ester Solid Lipid Nanoparticles for the Management of Hypercholesterolemia: An ex vivo Study

BACKGROUND: Phytostanols are naturally occurring compounds that reduce blood cholesterol levels significantly. However, their aqueous insolubility poses formulation challenges. AIM: To formulate and characterize solid lipid nanoparticle carriers for phytostanol esters to enhance the bioavailability...

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Detalles Bibliográficos
Autores principales: Shrestha, Sony Chandi, Ghebremeskel, Kebreab, White, Kenneth, Minelli, Caterina, Tewfik, Ihab, Thapa, Panna, Tewfik, Sundus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955784/
https://www.ncbi.nlm.nih.gov/pubmed/33727810
http://dx.doi.org/10.2147/IJN.S276301