Cargando…

Dexmedetomidine Alleviates LPS-Induced Neuronal Dysfunction by Modulating the AKT/GSK-3β/CRMP-2 Pathway in Hippocampal Neurons

OBJECTIVE: Dexmedetomidine, an α2-adrenergic receptor agonist, mitigates cognitive dysfunction in elderly patients after surgery with general anesthesia. However, the underlying mechanism by which dexmedetomidine reduces cognitive dysfunction remains to be fully elucidated. The aim of this study was...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, Wei, Zhang, Chunyuan, Long, Qingshan, Li, Yalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955869/
https://www.ncbi.nlm.nih.gov/pubmed/33727816
http://dx.doi.org/10.2147/NDT.S297365