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Precision genome editing in plants via gene targeting and subsequent break‐induced single‐strand annealing

Genome editing via artificial nucleases such as CRISPR/Cas9 has become popular in plants now. However, small insertions or deletions are major mutations and nucleotide substitutions rarely occur when DNA cleavage is induced. To induce nucleotide substitutions, a base editor utilizing dead or nickase...

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Detalles Bibliográficos
Autores principales: Endo, Masaki, Iwakami, Satoshi, Toki, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955887/
https://www.ncbi.nlm.nih.gov/pubmed/33001567
http://dx.doi.org/10.1111/pbi.13485