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Dictyostelium Differentiation-Inducing Factor-1 Promotes Glucose Uptake, at Least in Part, via an AMPK-Dependent Pathway in Mouse 3T3-L1 Cells

Differentiation-inducing factor-1 (DIF-1) is a chlorinated alkylphenone (a polyketide) found in the cellular slime mold Dictyostelium discoideum. DIF-1 and its derivative, DIF-1(3M) promote glucose consumption in vitro in mammalian cells and in vivo in diabetic rats; they are expected to be the lead...

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Detalles Bibliográficos
Autores principales: Kubohara, Yuzuru, Homma, Yoshimi, Shibata, Hiroshi, Oshima, Yoshiteru, Kikuchi, Haruhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956221/
https://www.ncbi.nlm.nih.gov/pubmed/33669058
http://dx.doi.org/10.3390/ijms22052293