Molecular goniometers for single-particle cryo-electron microscopy of DNA-binding proteins

Correct reconstruction of macromolecular structure by cryo-electron microscopy (cryo-EM) relies on accurate determination of the orientation of single-particle images. For small (<100 kDa) DNA-binding proteins, obtaining particle images with sufficiently asymmetric features to correctly guide ali...

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Detalles Bibliográficos
Autores principales: Aksel, Tural, Yu, Zanlin, Cheng, Yifan, Douglas, Shawn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956247/
https://www.ncbi.nlm.nih.gov/pubmed/33077960
http://dx.doi.org/10.1038/s41587-020-0716-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956247/
https://www.ncbi.nlm.nih.gov/pubmed/33077960
http://dx.doi.org/10.1038/s41587-020-0716-8

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