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Molecular goniometers for single-particle cryo-electron microscopy of DNA-binding proteins
Correct reconstruction of macromolecular structure by cryo-electron microscopy (cryo-EM) relies on accurate determination of the orientation of single-particle images. For small (<100 kDa) DNA-binding proteins, obtaining particle images with sufficiently asymmetric features to correctly guide ali...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956247/ https://www.ncbi.nlm.nih.gov/pubmed/33077960 http://dx.doi.org/10.1038/s41587-020-0716-8 |