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Chemical-Genetic Interactions of Bacopa monnieri Constituents in Cells Deficient for the DNA Repair Endonuclease RAD1 Appear Linked to Vacuolar Disruption

Colorectal cancer is a common cancer worldwide and reduced expression of the DNA repair endonuclease XPF (xeroderma pigmentosum complementation group F) is associated with colorectal cancer. Bacopa monnieri extracts were previously found to exhibit chemical-genetic synthetic lethal effects in a Sacc...

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Detalles Bibliográficos
Autores principales: Huangteerakul, Chananya, Aung, Hsu Mon, Thosapornvichai, Thitipa, Duangkaew, Marisa, Jensen, Amornrat Naranuntarat, Sukrong, Suchada, Ingkaninan, Kornkanok, Jensen, Laran T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956252/
https://www.ncbi.nlm.nih.gov/pubmed/33668176
http://dx.doi.org/10.3390/molecules26051207