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Simulation of the In Vivo Fate of Polymeric Nanoparticles Traced by Environment-Responsive Near-Infrared Dye: A Physiologically Based Pharmacokinetic Modelling Approach

The application of physiologically based pharmacokinetic models to nanoparticles is still very restricted and challenging, owing to the complicated in vivo transport mechanisms involving nanoparticles, including phagocytosis, enhanced permeability and retention effects, cellular recognition, and int...

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Detalles Bibliográficos
Autores principales: Li, Lei, He, Haisheng, Jiang, Sifang, Qi, Jianping, Lu, Yi, Ding, Ning, Lin, Hai-Shu, Wu, Wei, Xiang, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956253/
https://www.ncbi.nlm.nih.gov/pubmed/33652827
http://dx.doi.org/10.3390/molecules26051271