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Methylselenol Produced In Vivo from Methylseleninic Acid or Dimethyl Diselenide Induces Toxic Protein Aggregation in Saccharomyces cerevisiae

Methylselenol (MeSeH) has been suggested to be a critical metabolite for anticancer activity of selenium, although the mechanisms underlying its activity remain to be fully established. The aim of this study was to identify metabolic pathways of MeSeH in Saccharomyces cerevisiae to decipher the mech...

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Detalles Bibliográficos
Autores principales: Dauplais, Marc, Bierla, Katarzyna, Maizeray, Coralie, Lestini, Roxane, Lobinski, Ryszard, Plateau, Pierre, Szpunar, Joanna, Lazard, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956261/
https://www.ncbi.nlm.nih.gov/pubmed/33668124
http://dx.doi.org/10.3390/ijms22052241