Inhibition of Autophagy Does Not Re-Sensitize Acute Myeloid Leukemia Cells Resistant to Cytarabine

Elevated activation of the autophagy pathway is currently thought to be one of the survival mechanisms allowing therapy-resistant cancer cells to escape elimination, including for cytarabine (AraC)-resistant acute myeloid leukemia (AML) patients. Consequently, the use of autophagy inhibitors such as...

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Detalles Bibliográficos
Autores principales: Visser, Nienke, Lourens, Harm Jan, Huls, Gerwin, Bremer, Edwin, Wiersma, Valerie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956277/
https://www.ncbi.nlm.nih.gov/pubmed/33652766
http://dx.doi.org/10.3390/ijms22052337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956277/
https://www.ncbi.nlm.nih.gov/pubmed/33652766
http://dx.doi.org/10.3390/ijms22052337

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