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Inhibition of Autophagy Does Not Re-Sensitize Acute Myeloid Leukemia Cells Resistant to Cytarabine
Elevated activation of the autophagy pathway is currently thought to be one of the survival mechanisms allowing therapy-resistant cancer cells to escape elimination, including for cytarabine (AraC)-resistant acute myeloid leukemia (AML) patients. Consequently, the use of autophagy inhibitors such as...
Autores principales: | Visser, Nienke, Lourens, Harm Jan, Huls, Gerwin, Bremer, Edwin, Wiersma, Valerie R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956277/ https://www.ncbi.nlm.nih.gov/pubmed/33652766 http://dx.doi.org/10.3390/ijms22052337 |
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