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HIV-1 Protease Inhibitors Slow HPV16-Driven Cell Proliferation through Targeted Depletion of Viral E6 and E7 Oncoproteins

SIMPLE SUMMARY: High-risk strains of human papillomavirus (HPV) such as HPV16 cause anogenital and oropharyngeal cancers, with HPV-associated cervical cancer being the fourth most common cancer worldwide and a major cause of death for women. Anti-HPV vaccines are available but coverage is low, and w...

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Detalles Bibliográficos
Autores principales: Park, Soyeong, Auyeung, Andrew, Lee, Denis L., Lambert, Paul F., Carchman, Evie H., Sherer, Nathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956332/
https://www.ncbi.nlm.nih.gov/pubmed/33668328
http://dx.doi.org/10.3390/cancers13050949