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1,2,4-Oxadiazole-Based Bio-Isosteres of Benzamides: Synthesis, Biological Activity and Toxicity to Zebrafish Embryo

To discover new compounds with broad spectrum and high activity, we designed a series of novel benzamides containing 1,2,4-oxadiazole moiety by bioisosterism, and 28 benzamides derivatives with antifungal activity were synthesized. These compounds were evaluated against four fungi: Botrytis cinereal...

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Detalles Bibliográficos
Autores principales: Yang, Sen, Ren, Chao-Li, Ma, Tian-Yang, Zou, Wen-Qian, Dai, Li, Tian, Xiao-Yu, Liu, Xing-Hai, Tan, Cheng-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956408/
https://www.ncbi.nlm.nih.gov/pubmed/33673430
http://dx.doi.org/10.3390/ijms22052367