Contribution of Particle-Induced Lysosomal Membrane Hyperpolarization to Lysosomal Membrane Permeabilization

Lysosomal membrane permeabilization (LMP) has been proposed to precede nanoparticle-induced macrophage injury and NLRP3 inflammasome activation; however, the underlying mechanism(s) of LMP is unknown. We propose that nanoparticle-induced lysosomal hyperpolarization triggers LMP. In this study, a rap...

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Detalles Bibliográficos
Autores principales: Ziglari, Tahereh, Wang, Zifan, Holian, Andrij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956429/
https://www.ncbi.nlm.nih.gov/pubmed/33668885
http://dx.doi.org/10.3390/ijms22052277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956429/
https://www.ncbi.nlm.nih.gov/pubmed/33668885
http://dx.doi.org/10.3390/ijms22052277

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