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Response and Toxicity to Cytarabine Therapy in Leukemia and Lymphoma: From Dose Puzzle to Pharmacogenomic Biomarkers

SIMPLE SUMMARY: In this review, the authors propose a crosswise examination of cytarabine-related issues ranging from the spectrum of clinical activity and severe toxicities, through updated cellular pharmacology and drug formulations, to the genetic variants associated with drug-induced phenotypes....

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Detalles Bibliográficos
Autores principales: Di Francia, Raffaele, Crisci, Stefania, De Monaco, Angela, Cafiero, Concetta, Re, Agnese, Iaccarino, Giancarla, De Filippi, Rosaria, Frigeri, Ferdinando, Corazzelli, Gaetano, Micera, Alessandra, Pinto, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956511/
https://www.ncbi.nlm.nih.gov/pubmed/33669053
http://dx.doi.org/10.3390/cancers13050966