Anti-Tumor Effects of a Penetratin Peptide Targeting Transcription of E2F-1, 2 and 3a Is Enhanced When Used in Combination with Pemetrexed or Cisplatin

SIMPLE SUMMARY: The E2F family of transcription factors are essential for cell proliferation, differentiation, and DNA repair. They are commonly overexpressed or dysregulated in cancer as a consequence of inactivation or mutations in the retinoblastoma protein. Therefore, one or more of the activati...

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Detalles Bibliográficos
Autores principales: Rather, Gulam Mohmad, Anyanwu, Michael, Minko, Tamara, Garbuzenko, Olga, Szekely, Zoltan, Bertino, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956530/
https://www.ncbi.nlm.nih.gov/pubmed/33652640
http://dx.doi.org/10.3390/cancers13050972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956530/
https://www.ncbi.nlm.nih.gov/pubmed/33652640
http://dx.doi.org/10.3390/cancers13050972

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