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MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling
SIMPLE SUMMARY: The PTS signaling (PI3K/AKT, TGF-β, and STAT3 Signaling) networks, regulated by microRNA-21, play roles in lipogenic factor regulation, tumor suppressor modulation and oncogenic activation. Our zebrafish model recreates the development of hepatocellular carcinoma (HCC) due to nonalco...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956552/ https://www.ncbi.nlm.nih.gov/pubmed/33668153 http://dx.doi.org/10.3390/cancers13050940 |