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MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling

SIMPLE SUMMARY: The PTS signaling (PI3K/AKT, TGF-β, and STAT3 Signaling) networks, regulated by microRNA-21, play roles in lipogenic factor regulation, tumor suppressor modulation and oncogenic activation. Our zebrafish model recreates the development of hepatocellular carcinoma (HCC) due to nonalco...

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Detalles Bibliográficos
Autores principales: Lai, Chi-Yu, Yeh, Kun-Yun, Lin, Chiu-Ya, Hsieh, Yang-Wen, Lai, Hsin-Hung, Chen, Jim-Ray, Hsu, Chia-Chun, Her, Guor Mour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956552/
https://www.ncbi.nlm.nih.gov/pubmed/33668153
http://dx.doi.org/10.3390/cancers13050940