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Multi-Omics Data Analysis of Gene Expressions and Alterations, Cancer-Associated Fibroblast and Immune Infiltrations, Reveals the Onco-Immune Prognostic Relevance of STAT3/CDK2/4/6 in Human Malignancies

SIMPLE SUMMARY: Signal transducer and activator of transcription 3 (STAT3)/Cyclin-dependent kinases are multifunctional proteins that play instrumental roles in carcinogenesis. However, the genetic alterations of the STAT3/CDK2/4/6 signaling axis and its role in predicting immune infiltration and im...

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Detalles Bibliográficos
Autores principales: Lawal, Bashir, Lin, Li-Ching, Lee, Jih-Chin, Chen, Jia-Hong, Bekaii-Saab, Tanios S., Wu, Alexander T. H., Ho, Ching-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956610/
https://www.ncbi.nlm.nih.gov/pubmed/33668805
http://dx.doi.org/10.3390/cancers13050954