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Doxorubicin Loaded PLGA Nanoparticle with Cationic/Anionic Polyelectrolyte Decoration: Characterization, and Its Therapeutic Potency

Optimized Doxorubicin hydrochloride (DOX) loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles (DPN) were prepared by controlling the water/oil distribution of DOX at different pH solutions and controlling the electrostatic interaction between DOX and different terminated-end PLGAs. Furthermore...

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Detalles Bibliográficos
Autores principales: Tsai, Li-Hui, Yen, Chia-Hsiang, Hsieh, Hao-Ying, Young, Tai-Horng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956616/
https://www.ncbi.nlm.nih.gov/pubmed/33668941
http://dx.doi.org/10.3390/polym13050693